产品说明
一般描述
Transfection Reagent I comprises the cationic lipid 1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride (DOTAP) and the neutral lipid DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine. DOTAP is a surfactant with double chain quaternary ammonium. The DOTAP/DOPE liposome takes lamellar and inverted hexagonal structures.
应用
Transfection Reagent I has been used in the preparation of liposomes along with cholesterol for fluorescence-based live-cell imaging studies in the mouse embryonic fibroblasts cells. It may be used for the transfection of DNAzyme (Dz13) into veins.
生化/生理作用
Transfection Reagent I is used in large unilamellar cationic vesicles (LUVs) preparation and lipoplex generation. It improves transfection efficiency. DOTAP/DOPE (1,2-dioleoyloxypropyl)-N,N,N-trimethylammonium chloride /(1,2-dioleoyl-sn-glycero-3-phosphoethanolamine) is safe transfection agent for human administration. It inhibits the blood vessel thickening and is a promising candidate for use in coronary artery bypass grafting (CABG).
包装
5 mL Clear Glass Sealed Ampule (790310P-500mg)
5 mL Clear Glass Sealed Ampule (790310P-200mg)
5 mL Clear Glass Sealed Ampule (790310P-25mg)
5 mL Clear Glass Sealed Ampule (790310P-10mg)
基本信息
NACRES | NA.25 |
产品性质
形式 | powder |
包装 | pkg of 1 × 10 mg (790310P-10mg) pkg of 2 × 100 mg (790310P-200mg) pkg of 5 × 100 mg (790310P-500mg) pkg of 1 × 25 mg (790310P-25mg) |
manufacturer/tradename | Avanti Polar Lipids 790310P |
运输 | dry ice |
储存温度 | −20℃ |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
闪点(F) | No data available |
闪点(C) | No data available |
Sigma-Aldrich