产品说明
一般描述
Lysophosphatidylinositol (LPI) is a bioactive lipid.
应用
16:0 Lyso PI (1-palmitoyl-2-hydroxy-sn-glycero-3-phosphoinositol) has been used as a lipid standard in the optimization of the liquid chromatography–mass spectrometry (LC-MS) method conditions and also has been used as lysophosphatidylinositol (LPI) substrates in lysophosphatidylinositol acyltransferase biochemical assay to assay lyso-phosphatidylinositol acyltransferase (LPIAT) activity of liver microsomes. It may also be used as synthetic LPI to compare its effect with LPI from liver in transferrin (Tf)mediated endocytosis.
生化/生理作用
Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.
Lysophosphatidylinositol (LPI) has the ability to modulate cancer cell migration. It can control the functions of endothelium. LPI can serve as an autocrine regulator of cell growth, hence its known to participate in cancer progression. It can stimulate signaling cascades, that are essential for survival, migration and proliferation of cells.
包装
2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850102P-500ug)
基本信息
| 经验(实验)分子式 | C25H52NO12P |
| 分子量 | 589.65 |
产品性质
| 测定 | >99% (LPI; may contain up to 10% of the 2-LPI isomer, TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 100 μg (with stopper and crimp cap (850102P-100ug)) pkg of 1 × 500 μg (with stopper and crimp cap (850102P-500ug)) |
| manufacturer/tradename | Avanti Polar Lipids 850102P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | [H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(O)COC(CCCCCCCCCCCCCCC)=O.[NH4+] |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | No data available |
| 闪点(C) | No data available |
Sigma-Aldrich
m.cnreagent.com
