产品说明
一般描述
Phosphatidic acid is obtained from glycerophospholipid with the help of phospholipase D. 08:0 PA/1,2-dioctanoyl-sn-glycero-3-phosphate (C8-PA) is an mammalian target of rapamycin (mTOR) activator.
应用
08:0 PA may be used to activate p-mTOR in order to assess whether the observed apoptotic effect of histone deacetylase inhibitors (HDACIs) is related to mammalian target of rapamycin (mTOR) pathway signaling.
生化/生理作用
Phosphatidic acid might serve as a modulator of phagocyte respiratory burst. It also acts as a precursor of diacylglycerol and lysophosphatidic acid. 08:0 PA/C8-PA has the ability to affect the phosphorylation of mammalian target of rapamycin (mTOR) and the viability of gallbladder carcinoma cells, that are treated with histone deacetylase inhibitors (HDACIs).
包装
5 mL Clear Glass Sealed Ampule (830842P-10mg)
5 mL Clear Glass Sealed Ampule (830842P-25mg)
基本信息
| 经验(实验)分子式 | C19H36O8PNa |
| 分子量 | 446.45 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 10 mg (830842P-10mg) pkg of 1 × 25 mg (830842P-25mg) |
| manufacturer/tradename | Avanti Polar Lipids 830842P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | [H][C@@](COP([O-])(O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[Na+] |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
Sigma-Aldrich
m.cnreagent.com
