产品说明
一般描述
Sphingosine is the most bioactive sphingoid and a constituent of cell membrane. NBD sphingosine is a derivative of sphingosine tagged with the fluorophore, 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) group.
应用
NBD Sphingosine or omega(7-nitro-2-1,3-benzoxadiazol-4-yl)(2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol has been used to measure sphingosine kinase 1 (SPHK1) and sphingosine kinase 2 (SPK2) activity. NBD Sphingosine may be used as a negative control to determine the binding of Atg12-Atg5 conjugate with phosphatidylethanolamine(PE)-containing liposomes and to label sphingosine kinase 1 (SphK1) to determine its role in endocytic membrane trafficking.
生化/生理作用
Sphingosine is the precursor of ceramide. It plays a major role as a selective inhibitor of protein kinase C.
包装
5ML Amber Glass Screw Cap Vial (810205P-50UG)
5 mL Amber Glass Screw Cap Vial (810205P-250UG)
基本信息
| 经验(实验)分子式 | C24H39N5O5 |
| 分子量 | 477.60 |
| NACRES | NA.25 |
产品性质
| 测定 | >99% (TLC) |
| 形式 | powder |
| 包装 | pkg of 1 × 250 μg (810205P-250ug) pkg of 1 × 50 μg ( |
| manufacturer/tradename | Avanti Polar Lipids 810205P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21 |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
