hex-5-yn-1-yl 4-((3S,5S)-3-hydroxy-10, 13-dimethyl-1,2,3,4,5,7,8,9,10,11,12,13,14,15,16,17-hexadecahydrospiro[cyclopenta[a]phenanthrene-6,3′-diazirin]-17-yl)pentanoate

PhotoClick Cholesterol

品牌

Avanti

CAS

1485490-47-8

货号

700147P

包装型号

规格纯度

Hex-5′-ynyl 3β-hydroxy-6-diazirinyl-5α-cholan-24-oate, powder

参考价格

2432.79 元 *本价格含增值税费

促销

数量

产品名称：

1485490-47-8
PhotoClick Cholesterol
hex-5-yn-1-yl 4-((3S,5S)-3-hydroxy-10, 13-dimethyl-1,2,3,4,5,7,8,9,10,11,12,13,14,15,16,17-hexadecahydrospiro[cyclopenta[a]phenanthrene-6,3′-diazirin]-17-yl)pentanoate

产品介绍：

产品说明

一般描述

PhotoClick Cholesterol is a clickable, photoreactive sterol probe for use in combination with quantitative mass spectrometry to globally map cholesterol-protein interactions directly in living cells. In addition to the UV-activatable cross-linking diazirine group that reacts with proteins, the sterol contains an alkyne group for incorporation of reporter and affinity tags through click-chemistry.
PhotoClick Cholesterol is a synthetic analog of cholesterol and is photoreactive. It comprises the alkyne group.

应用

PhotoClick Cholesterol has been used:

in lysosome-associated membrane protein 1 (LAMP1) crosslinking studies
as an analog of cholesterol in binding and competition assay of sterol binding proteins from yeast
as a conjugate with the ectodomain of lysosomal integral membrane protein-2 (LIMP-2)

生化/生理作用

PhotoClick Cholesterol serves as a probe for tracking cholesterol-binding proteins. The copper-catalyzed azide-alkyne cycloaddition is the basis for its probe functionality. The alkyne group is essential for the click chemistry property. Its binding to partners is mediated by photocrosslinking.

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-250ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (700147P-100ug)

基本信息

经验(实验)分子式	C₃₀H₄₆N₂O₃
分子量	482.70
NACRES	NA.25

产品性质

测定	>99% (TLC)
形式	powder
包装	pkg of 1 × 100 μg (with stopper and crimp cap (700147P-100ug)) pkg of 1 × 250 μg (with stopper and crimp cap (700147P-250ug))
manufacturer/tradename	Avanti Polar Lipids 700147P
运输	dry ice
储存温度	−20℃

安全信息

储存分类代码

13 - Non Combustible Solids