Monoclonal Anti-Interleukin-4-R-Phycoerythrin antibody produced in mouse

产品说明

特异性

The conjugates will identify and quantitate cells containing intracellular forms of human IL-4.

免疫原

recombinant human IL-4

生化/生理作用

Interleukin-4 (IL-4) is a T cell derived chemokine that stimulates the Th2 mediated immune response and proliferation of B cells. The effects of IL-4 are mediated by two types of receptors, type I receptor consisting of IL-4Rα and common γ chain and type II receptor composed of IL-4Rα and IL-13Rα1. The signaling stimulated by IL-4 leads to activation of JAK/STAT6 and IRS-mediated PI3K/Akt pathway. IL-4 is responsible for endocytic activity of macrophages, chemotaxis of leukocytes in response to inflammation, angiogenesis and regulation of nitric oxide metabolism in macrophages. Conjugation of R-Phycoerythrin to the antibody enables its use in immunofluorescent techniques.

外形

25 μg of antibody in 1.0 mL of saline containing up to 0.5% bovine serum albumin. Contains 0.1% sodium azide as a preservative.

制备说明

Purified antibody is conjugated to R-phycoerythrin (PE).

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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