Atheronal B

产品说明

一般描述

Atheronal-B is generated by the intramolecular aldolization of atheronal-A and this interconversion is rapid. It is present in plasma and is well detectable. Atheronal A and B are also referred to as cholesterol 5,6-secosterols.
Atheronal molecules may be a  new association, in the already complex inter-relationship, between inflammation, cholesterol oxidation, the tissue macrophage, and atherosclerosis.

生化/生理作用

Atheronal-B levels are elevated in patients with cardiovascular disease like atherosclerosis. Atheronal A and B favor misfolding of α-synuclein, apolipoprotein-B100 and β-amyloid by adding an aldehyde group to the lysine side chain. In addition, atheronals also modify the cationic property of myelin basic protein (MBP) leading to structural change, which contributes directly to the pathogenesis of multiple sclerosis.

包装

5 mL Amber Glass Screw Cap Vial (700089P-1mg)

基本信息

产品性质

安全信息