产品说明
一般描述
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
特异性
Other species have not been tested.
The antibody reacts with the 70 kDa serotonin transporter protein.
免疫原
Epitope: Center region
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.
应用
This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
质量
Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.
目标描述
70 kDa
联系
Replaces: AB1594P
外形
Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.
Antigen Affinity Purified
储存及稳定性
Store at 2-8°C for 1 year from date of receipt.
分析说明
Control
Western Blot : Human lung lysate.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity (predicted by homology) | human (100% homology), rat (100% homology), bovine (100% homology), chimpanzee (100% homology), horse (100% homology), mouse (100% homology), monkey (100% homology), sheep (100% homology) |
浓度 | 1 mg/mL |
technique(s) | western blot: suitable |
UniProt登记号 | P31645 |
运输 | wet ice |
Gene Information | human ... HTT(3064) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich