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位置:首页 > 品牌 > Sigma-Aldrich > Milli-Mark® Anti-CD117 Antibody, c-kit-PE, clone 104D2

Milli-Mark® Anti-CD117 Antibody, c-kit-PE, clone 104D2

品牌
Sigma-Aldrich
货号
FCMAB214P
规格纯度
clone 104D2, Milli-Mark®, from mouse
参考价格
4681.07 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Milli-Mark® Anti-CD117 Antibody, c-kit-PE, clone 104D2
Mast/stem cell growth factor receptor, SCFR, Tyrosine-protein kinase Kit, Proto-oncogene c-Kit
产品介绍:

产品说明

一般描述

CD117 is a 145 kDa transmembrane protein which belongs to the class III receptor tyrosine kinase family. The extracellular region consists of five immunoglobulin-like domains where the second and third loops are thought to be involved in ligand binding (Ashman, 1997; Bühring, 1995). CD117 has been shown to be a marker for tissue mast cells, hematopoietic stem cells, and progenitor cells in normal human bone marrow. The majority of CD117-positive marrow cells (50-70%) co-express CD34 and comprise progenitor cells and their precursors of all hematopoietic lineages. Apart from mast cells, CD117 is essentially absent from mature hematopoietic cells. Although CD117 is primarily a marker for non-lymphoid progenitor cells in the hematopoietic cells/tissues, including melanocytes, embryonic brain, and the reproductive system (Ashman, 1997). Anti-CD117, 104D2, was included in the Sixth International Workshop and Conference on Human Leucocyte differentiation Antigens, and studies by different laboratories confirmed its reactivity with CD117 (Ashman, 1997).

特异性

Antibody recognizes Human CD117 antigen.

免疫原

MOLM-1 megakaryocytic cell line.

应用

Milli-Mark Anti-CD117 Antibody, c-kit-PE, clone 104D2 detects level of CD117 & has been published & validated for use in FC.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology

质量

Evaluated by flow cytometry using TF-1 cells

目标描述

145 kDa (Ashman, 1997; Buhring, 1995)

外形

Protein A purified
Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

储存及稳定性

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

分析说明

Control
TF-1 cells

法律信息

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物PE
抗体形式purified antibody
antibody product typeprimary antibodies
克隆104D2, monoclonal
species reactivityhuman
manufacturer/tradenameMilli-Mark®
technique(s)flow cytometry: suitable
同位素/亚型IgG1κ
NCBI登记号NP_000213
UniProt登记号P10721
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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