脯氨酸四唑催化剂

产品名称：

33878-70-5
(S)-(–)-5-(2-Pyrrolidinyl)-1H-tetrazole
Proline Tetrazole Catalyst
(S)-(–)-2-Tetrazol-5-ylpyrrolidine
(S)-5-(吡咯烷-2-基)-1H-四唑
脯氨酸四唑催化剂
(S)-(–)-2-四唑-5-基吡咯烷

产品介绍：

产品说明

应用

Organocatalyst used for:

Direct asymmetric aldol reactions between acetone and aldehydes yielding β -hydroxy ketone and for synthesizing 1,1,1-trichloro-2-alkanols
Mannich reactions for synthesis fo α -amino acids and generation of 1,4-diamines
Conjugate additions of malonates to enones

(S)-(−)-5-(2-Pyrrolidinyl)-1H-tetrazole can be used as an organocatalyst:

To prepare enantioselective chiral 1,2-oxazines from achiral ketones via an intramolecular Wittig reaction.
To synthesize diastereoselective Michael addition products by addition of aliphatic aldehydes to β-nitrostyrene.
In the direct asymmetric α-fluorination of linear and branched aldehydes using N-fluorobenzenesulfonamide as the fluorinating agent.

包装

100 mg in clear glass bottle
500 mg in amber glass bottle

基本信息

经验(实验)分子式	C₅H₉N₅
分子量	139.16
MDL编号	MFCD10000886
PubChem化学物质编号	329760905
NACRES	NA.22

产品性质

质量水平	100
测定	96%
旋光性	[α]20/D -9.0°, c = 1 in methanol
mp	253-258 ℃
SMILES string	C1CN[C@@H](C1)c2nnn[nH]2
InChI	1S/C5H9N5/c1-2-4(6-3-1)5-7-9-10-8-5/h4,6H,1-3H2,(H,7,8,9,10)/t4-/m0/s1
InChI key	XUHYQIQIENDJER-BYPYZUCNSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H301 - H315 - H319 - H335
预防措施声明	P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类	Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges