产品说明
特异性
By Western blot MAB1645 recognizes a single protein having a relative molecular weight of 300 kD. Reacts to mammalian skeletal muscle dystrophin. Shows no staining of mdx mouse muscle. Labels normal human muscle but not Duchenne muscle.
STAINING PATTERN:
On cryostat sections of normal mouse diaphragm MAB1645 gives strong immunofluorescence staining of the entire sarcolemma, with particularly strong staining of neuromuscular junctions.
SPECIES REACTIVITY:
Labels skeletal muscle from rat, chicken and Xenopus laevis. Labels cardiac muscle from rat and normal, but not mdx, mouse. Also labels smooth muscle from chicken gizzard.
免疫原
Peripheral membrane proteins extracted from Torpedo postsynaptic membranes.
应用
Anti-Dystrophin Antibody, clone 1808 detects level of Dystrophin & has been published & validated for use in WB, IH.
Western blot
Immunohistochemistry
Optimal working dilutions must be determined by the end user.
外形
Liquid in 0.02 M phosphate buffer (pH 7.6), 250 mM NaCl with 0.1% sodium azide.
Format: Purified
储存及稳定性
Maintain at -20ºC for up to 12 months in convenient aliquots. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | 1808, monoclonal |
species reactivity | chicken, rat, mouse, human |
manufacturer/tradename | Chemicon® |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NM_000109.2 NM_004006.1 NM_004007.1 NM_004009.2 NM_004010.2 NM_004011.2 NM_004012.2 NM_004013.1 NM_004014.1 NM_004015.1 NM_004016.1 NM_004017.1 NM_004018.1 NM_004019.2 NM_004020.1 NM_004021.1 NM_004022.1 NM_004023.1 |
UniProt登记号 | P11532 |
运输 | dry ice |
Gene Information | human ... DMD(1756) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich