Rubitecan

产品名称：

91421-42-0
Rubitecan
9-Nitrocamptothecin

产品介绍：

产品说明

包装

50 mg in poly bottle
10 mg in glass insert

生化/生理作用

Topoisomerase I inhibitor. Rubitecan induces protein- linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of action makes rubitecan a potential chemotherapeutic agent, and it has been used with some success against refractory pancreatic cancer.

基本信息

经验(实验)分子式	C₂₀H₁₅N₃O₆
分子量	393.35
MDL编号	MFCD06656294
PubChem化学物质编号	329824025

产品性质

生物来源	synthetic (organic)
质量水平	100
测定	≥98% (HPLC)
形式	powder
mp	182-186 ℃
溶解性	DMSO: 1 mg/mL
储存温度	room temp
SMILES string	CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5c(cccc5nc34)[N+]([O-])=O)C2=O
InChI	1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1
InChI key	VHXNKPBCCMUMSW-FQEVSTJZSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)