产品说明
包装
50 mg in poly bottle
10 mg in glass insert
生化/生理作用
Topoisomerase I inhibitor. Rubitecan induces protein- linked DNA single strand breaks, blocking DNA and RNA synthesis in dividing cells. This mode of action makes rubitecan a potential chemotherapeutic agent, and it has been used with some success against refractory pancreatic cancer.
基本信息
| 经验(实验)分子式 | C20H15N3O6 |
| 分子量 | 393.35 |
| MDL编号 | MFCD06656294 |
| PubChem化学物质编号 | 329824025 |
产品性质
| 生物来源 | synthetic (organic) |
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| mp | 182-186 ℃ |
| 溶解性 | DMSO: 1 mg/mL |
| 储存温度 | room temp |
| SMILES string | CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5c(cccc5nc34)[N+]([O-])=O)C2=O |
| InChI | 1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1 |
| InChI key | VHXNKPBCCMUMSW-FQEVSTJZSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
