产品说明
应用
Can be used as a control in immunoblotting and in protein binding assays.
生化/生理作用
Ral B has been implicated in invasion and metastasis of human cancer cells. Reports have shown that depletion of Ral B by siRNA results in significantly reduced migration rates of tumor cells, while constitutively active Ral B promoted migration.
Ral B (21 kDa, native), a member of the Ras-like GTP binding protein family, is a crucial link in intracellular signaling cascades.
其他说明
GST-tagged Ras-like fusion protein
外形
Supplied as a solution in 50 mM Tris, pH 7.5, containing 150 mM sodium chloride, 10 mM magnesium chloride, 1 mM DTT, and 10% glycerol.
基本信息
MDL编号 | MFCD03792555 |
NACRES | NA.56 |
产品性质
质量水平 | 200 |
重组 | expressed in E. coli |
形式 | buffered aqueous glycerol solution |
UniProt登记号 | P11234 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... RALB(5899) |
Sigma-Aldrich