产品说明
一般描述
Monoclonal Anti-hnRNP-A2/B1 (mouse IgG2a isotype) is derived from the DP3B3 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with recombinant human hnRNP-A2. hnRNP-A2/B1 proteins are located in the nucleus of most tissues cells. However, the hnRNP-A2 protein is found also in the cytoplasm of skin and esophagus cells. In rat brain, hnRNP-A2/B1 proteins are found in neurons in the cerebral cortices, hippocampal formation, olfactory regions, caudate-putamin and the supraoptic nucleus of the hypothalamus.
免疫原
recombinant human hnRNP-A2.
应用
Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
生化/生理作用
In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats).
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD03845440 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | DP3B3, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~36 kDa |
| species reactivity | rat, hamster, mouse, human, canine, chicken, monkey, bovine |
| technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable microarray: suitable western blot: 1-2 μg/mL using total cell extract from 293T cell line |
| 同位素/亚型 | IgG2a |
| UniProt登记号 | P22626 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HNRNPA2B1(3181) mouse ... Hnrnpa2b1(53379) rat ... Hnrnpa2b1(362361) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
