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Anti-SNAT2

品牌
Sigma-Aldrich
货号
ABN1734
包装型号
规格纯度
from rabbit
参考价格
3507.4 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-SNAT2
Sodium-coupled neutral amino acid transporter 2, Amino acid transporter A2, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino acid transporter 2
产品介绍:

产品说明

一般描述

Sodium-coupled neutral amino acid transporter 2 (UniProt: Q9JHE5; also known as Amino acid transporter A2, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino acid transporter 2) is encoded by the Scl38a2 (also known as Ata2, Sa1, Sat2, Snat2) gene (Gene ID: 29642) in rat. Sodium-coupled neutral amino acid transporter 2 is a multi-pass membrane protein that functions as a sodium-dependent amino acid transporter and mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. It may also function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta. Its transport action is reported to be inhibited by N-methyl-D-glucamine and choline. It is enriched in the somatodendritic compartment of neurons and is also detected at the axonal shaft, but is excluded from the nerve terminal. It is also expressed in skeletal muscle and adipose tissue. Its levels are up-regulated upon amino acid deprivation that results from increased transcription and protein stabilization.

特异性

This polyclonal antibody detects sodium-coupled neutral amino acid transporter 2 (SNAT2) in rat brain. It targets an epitope within the first 65 amino acids.

免疫原

Epitope: N-terminus
GST-tagged recombinant fragment corresponding to the first 65 amino acids from te N-terminal region of rat Sodium-coupled neutral amino acid transporter 2 (SNAT2).

应用

Anti-SNAT2, Cat. No. ABN1734, is a highly specific rabbit polyclonal antibody that targets Sodium-coupled neutral amino acid transporter 2 and has been tested in Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blotting.
Research Category
Neuroscience
Immunofluorescence Analysis: A 1:150 dilution from a representative lot detected SNAT2 in rat cerebral cortex and human cerebellum tissue sections.

Immunocytochemistry Analysis: A representative lot detected SNAT2 in Immunocytochemistry applications (Grewal, S., et. al. (2009). J Biol Chem. 284(17):11224-36).

Western Blotting Analysis: A representative lot detected SNAT2 in Western Blotting applications (Yao, D., et. al. (2000). J Biol Chem. 275(30):22790-7; Melone, M., et. al. (2006). Neuroscience. 140(1):281-92; Grewal, S., et. al. (2009). J Biol Chem. 284(17):11224-36).

Immunohistochemistry Analysis: A representative lot detected SNAT2 in Immunohistochemistry applications (Melone, M., et. al. (2006). Neuroscience. 140(1):281-92).

质量

Evaluated by Immunofluorescence in rat brain sections.

Immunofluorescence Analysis: A 1:150 dilution of this antibody detected SNAT2 in rat brain tissue sections.

目标描述

55.55 kDa calculated.

外形

Format: Unpurified
Rabbit polyclonal antiserum with 0.05% sodium azide.
Unpurified
Rabbit polyclonal antiserum with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Stable for 1 year at -20°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式unpurified
antibody product typeprimary antibodies
克隆polyclonal
species reactivityrat
包装antibody small pack of 25 μL
technique(s)immunocytochemistry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG
NCBI登记号NP_851604
UniProt登记号Q9JHE5
运输ambient

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1

Sigma-Aldrich

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