产品说明
特异性
Recognizes endothelin ET-1 (10% cross-reactivity with ET-3) and when used in conjunction with CBL87 (anti-endothelin C-terminus) has a sensitivity of 0.06 pmol/L for ET-1.
应用
Development of Immunoradiometric assay (IRMA) for endothelin ET-1 which as a circulating plasma peptide has been associated with a variety of disease studies such as diabetes, hypertension, cardiogenic shock, acute myocardial infarction and uraemia.
Suitable for immunohistochemistry on frozen sections
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
CNS Control of Metabolism
Hormones & Receptors
Detect Endothelin-1 using this Anti-Endothelin-1 Antibody, clone IC4 validated for use in IC.
外形
Protein A purified
Liquid in 0.02 M PBS with 0.25 M NaCl, pH 7.6. Contains 0.1% sodium azide.
Format: Purified
储存及稳定性
For use within 1 month of purchase when stored at +4°C, for long-term storage, aliquot antibody into small volumes and store at -20°C.
分析说明
Control
Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
克隆 | IC4, monoclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | immunohistochemistry: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NM_001955.3 |
UniProt登记号 | P05305 |
运输 | wet ice |
Gene Information | human ... EDN1(1906) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich