产品说明
一般描述
Insulin receptor substrate 1 (IRS1) belongs to the IRS family. It is mapped to human chromosome 2q36.
Anti-IRS-1 Antibody detects endogenous levels of total IRS-1 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human IRS-1.
Immunogen Range: 289-338
生化/生理作用
Insulin receptor substrate 1 (IRS1) participates in the insulin signaling pathway. It is associated with type 2 diabetes (T2D). IRS1 regulates glucose homeostasis, body growth and peripheral insulin action.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
基本信息
| MDL编号 | MFCD01633547 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 131 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunofluorescence: 1:100-1:500 immunohistochemistry: 1:50-1:100 |
| NCBI登记号 | P35568 |
| UniProt登记号 | P35568 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IRS1(3667) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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