产品说明
应用
SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies.
包装
10 mg in ampule
生化/生理作用
SIB 1893 non-competitively inhibits glutamate-induced increase in Ca2+ at human metabotropic glutamate receptor 1 (hmGluR1).1 It also acts as a positive allosteric modulator of hmGluR4.2
Selective and noncompetitive mGlu5 metabotropic glutamate receptor antagonist.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
基本信息
| 经验(实验)分子式 | C14H13N |
| 分子量 | 195.26 |
| MDL编号 | MFCD02262120 |
| PubChem化学物质编号 | 24278718 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | >99% |
| 形式 | solid |
| 溶解性 | DMSO: 18 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | Cc1cccc(\C=C\c2ccccc2)n1 |
| InChI | 1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10+ |
| InChI key | SISOFUCTXZKSOQ-ZHACJKMWSA-N |
| Gene Information | human ... GRM1(2911), GRM5(2915) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 - H335 |
| 预防措施声明 | P302 + P352 - P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| 靶器官 | Respiratory system |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
