产品说明
应用
Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.
包装
5 mg in glass bottle
25 mg in poly bottle
生化/生理作用
Tyrphostin 51 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.
EGFR tyrosine kinase inhibitor.
特点和优势
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制备说明
5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.
基本信息
| 经验(实验)分子式 | C13H8N4O3 |
| 分子量 | 268.23 |
| MDL编号 | MFCD00133903 |
| PubChem化学物质编号 | 24278756 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 200 |
| 生物来源 | synthetic (organic) |
| 测定 | ≥98% |
| 形式 | powder |
| 效能 | 0.8 μM IC50 |
| 溶解性 | DMSO: soluble 5 mg of Tyrphostin 51 in 0.1 ml of solvent, clear, orange to red |
| 储存温度 | 2-8℃ |
| SMILES string | NC(\C(=C\c1cc(O)c(O)c(O)c1)C#N)=C(/C#N)C#N |
| InChI | 1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+ |
| InChI key | JKNOYWVMHPMBEL-UNXLUWIOSA-N |
| Gene Information | human ... CDK2(1017), EGFR(1956) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
Sigma-Aldrich
m.cnreagent.com
