产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
Toloxatone is a reversible monoamine oxidase A inhibitor (MAOI) and antidepressant. Toloxatone belongs to the aryloxazolidinones, a relatively new class of reversible monoamine oxidase A inhibitors (MAOI). Studies show that derivatives such as 3-aryloxazolidin-2-one (oxazolidinones), which are regularly used to treat gram positive infections, represent a new class of reversible as well as irreversible inhibitors for MAO-A and MAO-B enzymes that are able to inhibit protein synthesis and also used for neurodegenerative-type pathologies.
制备说明
Toloxatone is soluble in DMSO at a concentration that is greater than 10 mg/ml.
基本信息
经验(实验)分子式 | C11H13NO3 |
分子量 | 207.23 |
EC 号 | 249-522-2 |
MDL编号 | MFCD00865391 |
PubChem化学物质编号 | 329826767 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | solid |
储存条件 | desiccated |
溶解性 | DMSO: >10 mg/mL |
储存温度 | 2-8℃ |
SMILES string | Cc1cccc(c1)N2CC(CO)OC2=O |
InChI | 1S/C11H13NO3/c1-8-3-2-4-9(5-8)12-6-10(7-13)15-11(12)14/h2-5,10,13H,6-7H2,1H3 |
InChI key | MXUNKHLAEDCYJL-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich