产品说明
一般描述
TAK1 is an orphan nuclear receptor that represses the transcription of Gata1 and also inhibits signal transduction via T3R, RAR and RXR pathways. This orphan receptor also regulates PPARα-mediated gene expression in liver cells . Anti-TAK1 antibody recognizes TAK1 (70 kDa). Additional unidentified bands may be detected.
免疫原
synthetic peptide corresponding to amino acids 588-606 of human TAK1. The sequence is identical in mouse and Xenopus.
应用
Anti-TAK1 antibody is suitable for use in immunoblot (using whole-cell extracts from control MDA-MB-231 cells and MDA-MB-231 cells expressing shRNA to TAK1 ). The product can also be used for immunoprecipitation (1 μg using RIPA lysate (1 mg) from 3T3/HIR cells).
外形
Solution in 0.1 M Tris-glycine buffer, pH 7.4, containing 150 mM sodium chloride, 0.05% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02097469 |
| NACRES | NA.44 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 70 kDa |
| species reactivity | human, mouse |
| technique(s) | immunoprecipitation (IP): 1 μg/mL using lysate from 3T3/A31 cells western blot: 1 μg/mL using lysate from 3T3/A31 cells |
| UniProt登记号 | O43318 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... MAP3K7(6885) mouse ... Map3k7(26409) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
Sigma-Aldrich
m.cnreagent.com
