U-74389G

产品名称：

153190-29-5
U-74389G
21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]pregna-1,4,9[11]-triene-3,20-dione maleate salt

产品介绍：

产品说明

应用

U-74389G has been shown to significantly decrease the level of ethanol-induced gastric mucosal necrosis in portal hypertensive (PHT) rats. Furthermore, U-74389G has been widely used in animal models of ischemic injury and hypertension.

包装

100 mg in glass insert

生化/生理作用

Free radical lipid peroxidation inhibitor in cultured brain cells, monocytic THP1 cells, and LLC-PK1 cell layers.

制备说明

U-74389G is soluble in ethanol at 20 mg/ml and yields a clear, light yellow solution.

基本信息

经验(实验)分子式	C₃₇H₅₀N₆O₂ · C₄H₄O₄
分子量	726.90
MDL编号	MFCD01074991
PubChem化学物质编号	24278768
NACRES	NA.77

产品性质

溶解性	ethanol: soluble 20 mg/mL, clear, light yellow
储存温度	−20℃
SMILES string	OC(=O)\C=C/C(O)=O.[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)C1=CC[C@]4(C)[C@H](CC[C@@]24[H])C(=O)CN5CCN(CC5)c6cc(nc(n6)N7CCCC7)N8CCCC8
InChI	1S/C37H50N6O2.C4H4O4/c1-36-13-11-27(44)23-26(36)7-8-28-29-9-10-31(37(29,2)14-12-30(28)36)32(45)25-40-19-21-42(22-20-40)34-24-33(41-15-3-4-16-41)38-35(39-34)43-17-5-6-18-43;5-3(6)1-2-4(7)8/h11-13,23-24,28-29,31H,3-10,14-22,25H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t28-,29-,31+,36-,37-;/m0./s1
InChI key	ABCSSKWSUJMJCP-WQDFMEOSSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)