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Anti-VAMP-8 (N-terminal) antibody produced in rabbit

Anti-VAMP-8 (N-terminal) 兔抗

品牌
Sigma-Aldrich
货号
V7389
规格纯度
~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution
参考价格
4692 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-VAMP-8 (N-terminal) antibody produced in rabbit
Anti-Endobrevin
Anti-Vesicle-associated membrane protein 8
Anti-VAMP-8 (N-terminal) 兔抗
产品介绍:

产品说明

一般描述

Vesicle-associated membrane protein 8 (VAMP-8/endobrevin) is located at 2p11.2 on the human chromosome.

免疫原

Synthetic peptide corresponding to amino acids 1-16 located at the N-terminal of human VAMP8, conjugated to KLH. This sequence is highly conserved (~75%) in mouse and rat VAMP8.

应用

Anti-VAMP-8 (N-terminal) antibody has been used in immunoblotting, western blotting.

生化/生理作用

Vesicle-associated membrane protein 8 (VAMP-8/endobrevin) is as an endosomal v-SNARE (vesicles or granules-soluble NSF attachment protein receptors) involved in fusion between early and late endosomes. It can interact with syntaxin-7, syntaxin-8, and Vti1b (Vesicle transport through interaction with t-SNAREs homolog 1B) to form an endosomal fusion complex. VAMP8 interacts with syntaxin-2 and is involved in the terminal step of cytokinesis in mammalian cells. VAMP8 is the major vesicular v-SNARE of zymogen granules from pancreatic acinar cells and has been shown to be a general vesicular SNARE for regulated exocytosis of the exocrine system. For platelet release reaction VAMP8 is the primary v-SNARE.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~14 kDa
species reactivityhuman
增强验证recombinant expression
Learn more about Antibody Enhanced Validation
浓度~1.5 mg/mL
technique(s)western blot: 0.25-0.5 μg/mL using HEK-293T cells expressing human VAMP8.
UniProt登记号Q9BV40
运输dry ice
储存温度−20℃
Gene Informationhuman ... VAMP8(8673)
mouse ... Vamp8(22320)
rat ... Vamp8(83730)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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