产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.
WR-1065 is the active metabolite of the prodrug amifostine, generated by alkaline phosphatase. It is found to accumulate in many epithelial tissues. WR-1065 protects cellular membranes and DNA from free radical induced damage.
基本信息
| 经验(实验)分子式 | C5H14N2S · 2HCl |
| 分子量 | 207.16 |
| MDL编号 | MFCD00460339 |
| PubChem化学物质编号 | 329830444 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to off-white |
| 溶解性 | H2O: ≥20 mg/mL |
| 储存温度 | −20℃ |
| SMILES string | Cl.Cl.NCCCNCCS |
| InChI | 1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H |
| InChI key | XDRLRDHLCIFZIW-UHFFFAOYSA-N |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H302 - H318 |
| 预防措施声明 | P280 - P305 + P351 + P338 |
| 危险分类 | Acute Tox. 4 Oral - Eye Dam. 1 |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
