产品说明
特异性
Specific for human integrin beta 3 (other species not tested).
免疫原
Human integrin alphaVbeta3 heterodimer isolated from placenta.
应用
Research Category
Cell Structure
Research Sub Category
Integrins
Flow cytometry
Function-blocking of integrin beta3-mediated adhesion to ECM proteins.
Western blot (reducing conditions) Optimal working dilutions must be determined by end user.
Anti-Integrin β3 Antibody, clone B3A, azide free detects level of Integrin β3 & has been published & validated for use in FC, FUNC & WB.
目标描述
110 kDa
外形
Format: Purified
Protein A purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
储存及稳定性
Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Positive Control: U251 or D54 human cell lines. Membrane preps are recommended for western blots.
Human endothelium cells (expression of integrin alpha V beta 3 may need to be upregulated by phorbol esters stimulation). Skin (Basement Membrane)
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | B3A, monoclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable western blot: suitable |
NCBI登记号 | NM_000212.2 |
UniProt登记号 | P05106 |
运输 | wet ice |
Gene Information | human ... ITGB3(3690) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich