4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate

产品名称：

Phorbol 12-myristate 13-acetate
PMA
TPA
4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
12-O-Tetradecanoylphorbol 13-acetate

产品介绍：

产品说明

应用

Phorbol 12-Myristate 13-Acetate is suitable as an inducer of cell differentiation in monocytic cell lines such as U937 and THP-1.

生化/生理作用

Phorbol 12-Myristate 13-Acetate is a tumor-promoting phorbol ester. It regulates various processes such as gene transcription, cellular growth and differentiation, apoptosis, the immune response, and receptor desensitization via activating protein kinase C (PKC) signaling pathways. It promotes differentiation of human monocytic THP-1 cells to functional macrophages.

外形

C₃₆H₅₆O₈

储存及稳定性

2 years at -20°C

法律信息

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160405
NACRES	NA.41

产品性质

质量水平	100
manufacturer/tradename	Upstate^®
technique(s)	activity assay: suitable (kinase)
运输	wet ice

安全信息

象形图
警示用语：	Danger
危险声明	H300 + H310 + H330 - H315 - H318 - H351
预防措施声明	P201 - P202 - P280 - P302 + P352 + P310 - P304 + P340 + P310 - P305 + P351 + P338
危险分类	Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 2 Oral - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2
储存分类代码	6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK	WGK 3