产品说明
特异性
Reacts with c-met/HGFR (Hepatocyte growth factor receptor). The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor (HGF/SF) and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.
免疫原
Purified recombinant catalytic domain of human Met
应用
This Anti-c-met Antibody, clone 4AT44 is validated for use in WB for the detection of c-met.
Research Category
Signaling
Western Blot: 1:100-1:500.
ELISA (direct): 1:1,000
Optimal working dilutions must be determined by the end user.
Research Sub Category
Growth Factors & Receptors
联系
Replaces: 04-1051
外形
Protein G purified immunoglobulin. Liquid in PBS containing 0.09% sodium azide.
Format: Purified
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 4AT44, monoclonal |
species reactivity | mouse, human |
manufacturer/tradename | Chemicon® |
technique(s) | western blot: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NP_000236.2 |
UniProt登记号 | P08581 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich