产品说明
一般描述
This 145 kDa molecule is a member of the tyrosine kinase receptor family and is expressed by a majority of hematopoietic progenitor cells. The interaction of the mouse c-kit receptor and steel factor promotes proliferation and differentiation of hematopoietic progenitor cells. CD117 is also expressed by mast cells, and plays a role in signaling and activation of these cells.
特异性
Specifically recognizes mouse CD117, known as c-kit receptor, stem cell factor receptor and steel factor receptor.
应用
Flow Cytometry: 0.2 μg per 10e6 cells
Immunoprecipitation
Immunohistochemistry (Frozen)
Western blot
Blocking Ligand Binding
Optimal working dilutions must be determined by the end user.
Detect CD117 using this Anti-CD117 Antibody, clone ACK2 validated for use in FC, IH, IP, FUNC & WB.
Research Category
Stem Cell Research
Research Sub Category
Hematopoietic Stem Cells
Mesenchymal Stem Cells
目标描述
145 kDa
联系
Replaces: CBL1360P
外形
Format: Purified
The monoclonal is presented in phosphate buffered saline containing 10mM sodium azide.
Protein A purified
储存及稳定性
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
分析说明
Control
Skin tissue, normal breast epithelium, melanocytes, mast cells and glial cells
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | rat |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | ACK2, monoclonal |
species reactivity | mouse |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable |
input | sample type hematopoietic stem cell(s) sample type mesenchymal stem cell(s) |
同位素/亚型 | IgG2bκ |
NCBI登记号 | NM_000222.2 NM_001093772.1 |
UniProt登记号 | P10721 |
运输 | wet ice |
Gene Information | human ... KIT(3815) |
安全信息
储存分类代码 | 10 - Combustible liquids |
Sigma-Aldrich