产品说明
一般描述
c-Fos is an inducible transcription factor and a functional marker of activated neurons. It is induced in response to neurotransmitters and growth factors.
免疫原
Synthetic peptide directed towards the C terminal region of human FOS
应用
Anti-FOS produced in rabbit is suitable for western blotting at a concentration of 1.25 μg/ml.
生化/生理作用
c-Fos is a trans-acting factor that does not directly bind DNA. It interacts with AP-1 transcription factor, a step that is prerequisite for c-Fos-mediated gene expression. The role of c-Fos has been studied in activation of neurons, oncogenesis and inflammation of bone and skin.
序列
Synthetic peptide located within the following region: CTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLA
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 41 kDa |
| species reactivity | human, pig, mouse, rat, bovine, dog, sheep |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_005243 |
| UniProt登记号 | P01100 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOS(2353) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
