产品说明
一般描述
Eotaxin is a chemokine and belongs to the Th2 (T helper 2) cytokine family. It is expressed in many organs, such as heart, central nervous system and the cerebrospinal fluid. The associated gene (CCL11 (C-C motif chemokine ligand 11)) is mapped to human chromosome 17q12.
生化/生理作用
Eotaxin participates in immunoregulatory and inflammatory responses. It works as a chemoattractant for many immune cells, including eosinophils, basophils, myeloid cells and T-helper 2 lymphocytes. The eotaxin gene is associated with atopic dermatitis, allergic rhinitis, sinusitis, asthma, ulcerative colitis, gastrointestinal disorders and parasitic infections. It is also involved with the pathogenesis of ovarian and gastric cancer. Eotaxin plays a significant role in the aging processes.
外形
Sterile filtered and Lyophilized without additives.
重悬
Reconstituted in water to a concentration of 0.1-1 μg/μL. It is recommended that further dilutions be made into buffer containing carrier protein or medium containing serum.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
| MDL编号 | MFCD01093487 |
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥97% (HPLC) ≥97% (SDS-PAGE) |
| 形式 | lyophilized |
| 效能 | 10 ng/mL |
| 分子量 | ~8.3 kDa |
| 包装 | pkg of 20 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | endotoxin, tested |
| NCBI登记号 | P51671 |
| UniProt登记号 | P51671 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CCL11(6356) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
