产品说明
一般描述
Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase and it participates in the repair of DNA double-strand breaks. ATM is expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes. Increased ATM protein expression was reported in prostatic intraepithelial neoplasias (PINs) and some prostate cancer. ATM mutation has also been identified in mantle cell lymphoma, gastric cancer, lung adenocarcinoma, and breast cancer.
免疫原
Synthetic peptide derived from human ATM protein.
特点和优势
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外形
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
重组 | expressed in proprietary host |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | SP224, monoclonal |
species reactivity | human (tested) |
species reactivity (predicted by homology) | pig, mouse |
technique(s) | flow cytometry: 1:100 immunohistochemistry: 1:100 |
同位素/亚型 | IgG |
UniProt登记号 | Q13315 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | human ... ATM(472) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich