产品说明
一般描述
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5′ to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1 (NP_542380.1).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 35 |
| species reactivity | human |
| 浓度 | 6.18 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:100 immunoprecipitation (IP): 1:50-1:200 western blot: 1:500-1:2000 |
| UniProt登记号 | P27695 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... APEX1(328) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
