您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Anti-IL-1β converting enzyme

Anti-Caspase-1 (ab2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
PRS3463
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
4731.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-Caspase-1 (ab2) antibody produced in rabbit
Anti-ICE
Anti-Caspase 1, apoptosis-related cysteine peptidase (Interleukin 1, beta, convertase)
Anti-IL-1β converting enzyme
产品介绍:

产品说明

一般描述

Caspase-1 is also known as interleukin-1βconverting enzyme (ICE). It is located on chromosome 11q22.2. It has 10 exons, an N terminal CARD (caspase activation and recruitment domain), a large P20 subunit and a small P10 subunit. It is present in leukocytes, monocytes and epithelial cells.

免疫原

a 15 amino acid peptide from near the middle of human Caspase-1.

生化/生理作用

Caspase-1 can transform the pro-inflammatory cytokines, interleukin-1β (IL-1β) and IL-18 into their active forms. It participates in pyroptosis. It is overexpressed in the aorta of coronary atherosclerosis patients.It helps in host cell survival by inducing membrane biogenesis to restore the impairment caused by pore-forming toxins.

联系

The action of this antibody can be blocked using blocking peptide SBP3463.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide

基本信息

NACRESNA.41

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号P29466
运输dry ice
储存温度−20℃
Gene Informationhuman ... CASP1(834)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品