产品说明
一般描述
The 15.2 antibody reacts with human CD54, also known as ICAM-1 (Intercellular Adhesion Molecule 1), a 90-110 kDa cell surface glycoprotein that is inducibly expressed on both immune and endothelial cells. As its name implies, ICAM-1 participates in cell-cell adhesion between leukocytes and endothelial cells, facilitating leukocyte recruitment and transmigration at sites of inflammation. The ligands for ICAM-1 are also expressed on leukocyte and endothelial cells, and include Mac-1, fibrinogen, and a member of the integrin protein family, LFA-1 (CD11a).The 15.2 antibody may be used for analysis of ICAM-1 expression in human cells and tissues, and is reported to be cross-reactive with porcine ICAM-1.
This mouse monoclonal antibody Anti-CD54 (ICAM-1) (human), PE, clone 15.2 validated for use in western blotting, IHC & Flow Cytometry for the detection of CD54 (ICAM-1).
质量
The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.5 µg of this antibody detected CD54 (ICAM-1) in one million human peripheral blood monocytes.
外形
Size Exclusion Chromatography
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | PE |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | 15.2, monoclonal |
species reactivity | human |
包装 | pkg of 5 μL (0.5 μg/test) |
technique(s) | flow cytometry: suitable immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG1 |
UniProt登记号 | P05362 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich