产品说明
特异性
This antibody reacts with the 44 kDa antigen found on a sub-population of T cells and activated B cells. These CD28+ CD8 cells are now known to be cytotoxic T cell precursors. The antibody does not react with B cells, granulocytes or monocytes. The ligand for CD28 is CD80 (B7) which is found on activated B cells suggesting a role for CD28 in T and B cell interaction
FUSION PARTNER: SP2/0
免疫原
Human T lymphocytes
应用
To study the role of CD28 in T cell proliferation. The antibody will induce the proliferation of resting T lymphocytes.
This antibody will act in cell stimulation studies where it has been suggested that measuring T cell function in HIV infected asymptomatic patients may be an early indicator of AIDS, independent of CD4 + cell counts
Optimal working dilutions must be determined by the end user.
This Anti-CD28 Antibody, clone 15E8 is validated for use in FC, FUNC for the detection of CD28.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology
联系
Replaces: CBL517P
外形
Please see lot specific datasheet for product formulation. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Format: Purified
储存及稳定性
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C for up to one year.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | 15E8, monoclonal |
species reactivity | human |
should not react with | canine |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NM_006139.1 |
UniProt登记号 | P10747 |
运输 | wet ice |
Gene Information | human ... CD28(940) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | nwg |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich