产品说明
特异性
Clone 581 reacts with the class III CD34 epitope is resistant to neuraminidase, chymopapain and glycoprotease.
The antibody reacts with a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein which is expressed on haematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. CD34 may also play a role in the adhesion of specific antigens to endothelium.
应用
This Anti-CD34 Antibody, Class III, clone 581 is validated for use in FC for the detection of CD34 Class III.
Study of the Class III CD34 epitope by FACS
Optimal working dilutions must be determined by the end user.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology
外形
Protein G affinity chromatography. The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.
Format: Purified
储存及稳定性
For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | 581, monoclonal |
species reactivity | human |
manufacturer/tradename | Chemicon® |
technique(s) | flow cytometry: suitable |
同位素/亚型 | IgG1 |
NCBI登记号 | NM_001025109.1 NM_001773.2 |
UniProt登记号 | P28906 |
运输 | wet ice |
Gene Information | human ... CD34(947) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich