产品说明
一般描述
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
免疫原
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FAK (NP_722560.1).
外形
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
储存及稳定性
Store at -20℃. Avoid freeze / thaw cycles.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 114 119 120 39 48 63 99 |
| species reactivity | rat, mouse, human |
| 浓度 | 2.86 mg/ml |
| technique(s) | immunofluorescence: 1:50-1:200 immunohistochemistry: 1:50-1:200 immunoprecipitation (IP): 1:50-1:100 western blot: 1:500-1:2000 |
| UniProt登记号 | Q05397 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PTK2(5747) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
