产品说明
一般描述
FOS proteins are known to modulate cell growth and differentiation. FOSL2 is a leucine zipper transcription factor that regulates leptin expression in adipocytes.
Rabbit Anti-FOSL2 antibody recognizes zebrafish, human, chicken, mouse, rat, canine, and bovine FOSL2.
免疫原
Synthetic peptide directed towards the middle region of human FOSL2
应用
Rabbit Anti-FOSL2 antibody can be used for immunohistochemical (4-8μg/ml) and western blot (0.2-0.5μg/ml) applications.
生化/生理作用
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2, which encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
序列
Synthetic peptide located within the following region: PMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFY
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 35 kDa |
| species reactivity | human, bovine, rabbit, rat, dog, guinea pig, horse |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_005244 |
| UniProt登记号 | P15408 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOSL2(2355) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
