产品说明
一般描述
GATA binding protein 1 (GATA1) is a key hematopoietic transcription factor. It is part of the GATA transcription factor family and the gene encoding it is localized on human chromosome Xp11.23.
免疫原
Peptide with sequence C-DAEAYRHSPVFQ from the internal region of the protein sequence according to NP_002040.1.
生化/生理作用
GATA binding protein 1 (GATA1) plays a crucial role in erythroid and megakaryocyte differentiation and proliferation. It modulates the expression of genes and acts as an E-cadherin repressor. Mutations in the GATA1 gene have been linked to transient abnormal myelopoiesis (TAM) and myeloid leukemia of DS (ML-DS). The protein has anti-apoptotic functions in breast cancer.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
基本信息
| MDL编号 | MFCD02096392 |
| NACRES | NA.41 |
产品性质
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human, mouse, rat, canine |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| UniProt登记号 | P15976 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GATA1(2623) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H315 - H319 |
| 预防措施声明 | P305 + P351 + P338 |
| 危险分类 | Eye Irrit. 2 - Skin Irrit. 2 |
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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