产品说明
一般描述
Janus kinase 2 (JAK2) encodes a tyrosine kinase which belongs to the Jak family of protein kinases. The gene encoding this protein is localized on human chromosome 9p24.
免疫原
Peptide with sequence RVDQVRDNMAG, from the C-terminal region of the protein sequence according to AAC23653.1
生化/生理作用
Janus kinase 2 (JAK2) plays an important role in the activities of cytokine receptors. Overexpression of JAK2 results in neuroblastoma. Mutations in the gene have been linked to primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy.
特点和优势
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外形
Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | goat |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| UniProt登记号 | O60674 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... JAK2(3717) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 2 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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