Anti-MYC antibody produced in rabbit

产品说明

一般描述

The MYC (MYC proto-oncogene, bHLH transcription factor) gene is mapped to human chromosome 8q24.21. This gene encodes an oncogenic transcription factor and belongs to the MYC gene family. Anti-MYC antibody detects endogenous levels of total MYC protein.

免疫原

The antiserum was produced against synthesized peptide derived from human MYC.

Immunogen Range: 386-435

应用

Anti-MYC antibody produced in rabbit has been used in western blotting.

生化/生理作用

MYC proto-oncogene, bHLH transcription factor (MYC) is known to induce tumor growth in a variety of cancer types. c-MYC overexpression promotes DNA replication, transcription, translation and metabolism in cancer cells. Upregulation of this gene is observed in pancreatic ductal adenocarcinoma and diffuse large B-cell lymphoma (DLBCL).

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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