产品说明
一般描述
NOS1 (nitric oxide synthase 1) is one of the NOS (nitric oxide synthase) isoforms found in the heart. It is located on human chromosome 12q24.2-31. It is mainly localized in the sarcoplasmic reticulum (SR).
免疫原
Peptide sequence around aa. 850-854 (F-N-S-V-S), according to the protein NOS1.
应用
Anti-NOS1 (Ab-852) antibody has been used in immunocytochemistry .
生化/生理作用
NOS (nitric oxide synthase) produce nitric oxide in the heart.It regulates myocardial function and plays an important role in the remodeling of human (ICM) ischemic cardiomyopathy.
特点和优势
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目标描述
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD01092550 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~160 kDa |
species reactivity | human, rat, mouse |
浓度 | 1 mg/mL |
technique(s) | indirect immunofluorescence: 1:100-1:200 |
同位素/亚型 | IgG |
免疫原序列 | (F-N-S-V-S) |
NCBI登记号 | NP_000611.1 |
UniProt登记号 | P29475 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... NOS1(4842) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich