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Anti-NR3C1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700774
包装型号
规格纯度
参考价格
4713.83 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Anti-NR3C1 antibody produced in rabbit
GR
NR3C1
GCCR
GCR
GCRST
GRL
产品介绍:

产品说明

一般描述

This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175).

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human NR3C1 (NP_001191194.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 49-85
species reactivitymouse, human
浓度10.61 mg/ml
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号P04150
运输wet ice
储存温度−20℃
Gene Informationhuman ... NR3C1(2908)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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