产品说明
一般描述
FGFR1 (fibroblast growth factor receptor 1) gene codes for nine isoforms of FGFR1. It has 19 exons spanning 55kb DNA. It is located on human chromosome 8p11.1. Increased expression of FGFR1 is seen in midfacial membranous ossification sites. It is mostly present in hippocampal and dentate gyrus neurons.
免疫原
The antiserum was produced against synthesized peptide derived from human FGFR1 around the phosphorylation site of Tyr154.
Immunogen Range: 121-170
生化/生理作用
FGFR1 (fibroblast growth factor receptor 1) helps in the growth of the nervous system. This gene controls the skeletal development and bone homeostasis. FGFR1 mutations lead to craniosynostosis and facial abnormalities. Mutation in FGFR1 Ig-like domain II-III linker region (FGFR1 P252R) results in Pfeiffer syndrome.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 91 kDa |
| species reactivity | rat, human, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:40000 western blot: 1:500-1:1000 |
| NCBI登记号 | P11362 |
| UniProt登记号 | P11362 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FGFR1(2260) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
