产品说明
免疫原
Peptide sequence around phosphorylation site of tyrosine791 (P-V-Y(p)-L-D), according to the protein NTRK1.
特点和优势
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目标描述
Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
| MDL编号 | MFCD00239748 |
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~140 kDa |
| species reactivity | human, mouse, rat |
| 浓度 | 1 mg/mL |
| technique(s) | indirect immunofluorescence: 1:100-1:200 |
| 同位素/亚型 | IgG |
| 免疫原序列 | (P-V-YP-L-D) |
| NCBI登记号 | NP_001007793.1 |
| UniProt登记号 | P04629 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... NTRK1(4914) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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