产品说明
免疫原
Peptide sequence around aa. 491-495 (S-Y-Y-T-A), according to the protein ZAP70.
特点和优势
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目标描述
ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the zeta chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-zeta chain, which can mediate the transduction of extracellular stimuli into cellular effector functions.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~70 kDa |
species reactivity | mouse, human, rat |
浓度 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 |
同位素/亚型 | IgG |
免疫原序列 | (S-Y-Y-T-A) |
NCBI登记号 | NP_001070.2 |
UniProt登记号 | P43403 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... ZAP70(7535) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |