产品说明
一般描述
It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity.
生化/生理作用
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. Recombinant murine GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.
外形
Lyophilized from 10 mM Tris, pH 8.5
重悬
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20℃ to -80℃.
产品性质
| 生物来源 | rat |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (HPLC) ≥98% (SDS-PAGE) |
| 形式 | lyophilized |
| 效能 | ≥0.01 ng/mL |
| 分子量 | 14.5 kDa |
| 包装 | pkg of 20 μg |
| 杂质 | <0.1 EU/μg endotoxin, tested |
| 颜色 | white to off-white |
| UniProt登记号 | P01587 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | rat ... CSF2(12981) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
