产品说明
一般描述
The CD25 gene, also referred to as IL2RA (interleukin 2 receptor subunit α), is mapped to human chromosome 10p15. The gene spans a length of 48 kb with eight exons.
生化/生理作用
The interleukin 2 receptor subunit α (IL2RA) gene encodes the α-chain of the IL-2 receptor complex. This receptor complex, made up of α, β, and a common γ chain, binds to its ligand, IL-2, which is a crucial growth factor for T- and B-cells. This ligand-receptor complex plays an important role in the regulation of immune responses. Variation in the chromosomal region containing this gene is associated with type 1 diabetes. This region is also linked to autoimmune thyroid disease indicating its role in autoimmunity. IL2RA has been found to confer a risk for multiple sclerosis.
外形
Supplied in PBS with 0.09% (W/V) sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | crude ascites |
| antibody product type | primary antibodies |
| 克隆 | 7G7B6, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 30819 Da |
| species reactivity | human |
| technique(s) | western blot: 1:100-~1:800 |
| 同位素/亚型 | IgG2a |
| NCBI登记号 | NP_000408.1 |
| UniProt登记号 | P01589 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IL2RA(3559) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
