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1-Methyladenosine

品牌
Sigma-Aldrich
CAS
15763-06-1
货号
SMB00939
规格纯度
≥95% (HPLC)
参考价格
812.82 *本价格含增值税费
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数量
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产品名称:
15763-06-1
1-Methyladenosine
N1-Methyladenosine
产品介绍:

产品说明

一般描述

1-Methyladenosine, also known as M1A, belongs to the class of organic compounds known as purine nucleosides. Purine nucleosides are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety. 1-Methyladenosine is a strong basic compound (based on its pKa). Precise m6A mapping by m6A-CLIP/IP (briefly m6A-CLIP) revealed that a majority of m6A locates in the last exon of mRNAs in multiple tissues/cultured cells of mouse and human, and the m6A enrichment around stop codons is a coincidence that many stop codons locate round the start of last exons where m6A is truly enriched. The methylation of adenosine is directed by a large m6A methyltransferase complex containing METTL3 as the SAM-binding sub-unit. Insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1–3) are reported as a novel class of m6A readers.

应用

Metabolomics

基本信息

经验(实验)分子式C11H15N5O4
分子量281.27
MDL编号MFCD00038421

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
颜色 white
储存温度-10 to -25℃
SMILES stringCN1C=Nc2c(ncn2[C@@H]3O[C@@H](CO)[C@H](O)[C@@H]3O)C1=N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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