2,4,3′,5′-tetramethoxystilbene

产品名称：

24144-92-1
2,4,3′,5′-tetramethoxystilbene
1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene
2,3′,4,5′-Tetramethoxystilbene
2,4,3′,5′-四甲氧基二苯乙烯

产品介绍：

产品说明

包装

10 mg in glass bottle
50 mg in poly bottle

生化/生理作用

2,3′,4,5′-Tetramethoxystilbene, also known as TMS, is a selective and competitive inhibitor of cytochrome P450 1B. It is a synthetic trans-stilbene analog. TMS is an analog of resveratrol and is an anti-cancer agent. TMS is cytotoxic to gefitinib-resistant (G-R) non-small-cell lung cancer (NSCLC) cells. It binds to sarco/endoplasmic reticulum Ca²⁺-ATPase (SERCA) and promotes apoptosis and autophagy. TMS is also a selective inhibitor of CYP1B1.

基本信息

经验(实验)分子式	C₁₈H₂₀O₄
分子量	300.35
MDL编号	MFCD03428621
PubChem化学物质编号	329824983
NACRES	NA.79

产品性质

测定	≥98% (HPLC)
形式	powder
technique(s)	HPLC: suitable
颜色	white to yellow
储存温度	−20℃
SMILES string	COC1=CC(OC)=CC=C1/C=C/C2=CC(OC)=CC(OC)=C2
InChI	1S/C18H20O4/c1-19-15-8-7-14(18(12-15)22-4)6-5-13-9-16(20-2)11-17(10-13)21-3/h5-12H,1-4H3/b6-5+
InChI key	JDBCWSHYEQUBLW-AATRIKPKSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable